If you want to identify new candidate genes for a function/pathway/phenotype,
you can start search by submitting a set of known genes for the function/pathway/phenotype. These
submitted genes are used as 'seed genes' for network search. This search page collects closely
connected genes to the seed genes on AraNet by 'guilt-by-association' method and list the prioritized
genes by total edge weight score (sum of Log likelihood score) to the seed gene set. Highly ranked genes
are good candidates for new members of a function/pathway/phenotype of interest.
If you want to get a functional insight for an uncharacterized gene,
you can use its network neighbors. AraNet connects genes that are functionally associated. Therefore,
the uncharacterized gene may have similar function of its connected network neighbors. This search page
collects all known functional annotations (Gene Ontology Biological Process terms) among neighbors
of a query gene on AraNet, and then list the functional terms by the order of enrichment.
Back to Main |